The M√ľnchner Studienzentrum, Technical University Munich, School of Medicine, successfully hosted the ICN Steering Board Meeting and Annual General Meeting on October 25-26, 2022, shifting once more to an online format due to pandemic challenges. At the Steering Board Meeting, the SB members collaborated to shape the future of ICN, developing a strategic plan for 2023 and appointing new leadership. The subsequent Annual General Meeting, featuring 50 representatives from our global member institutions, focused on key performance indicators, decentralized clinical trials, machine learning in clinical research, real-world evidence, and presented an ICN workgroup report.